Oxidative Stress in Graves Disease and Graves Orbitopathy
نویسندگان
چکیده
منابع مشابه
Oxidative stress in graves' disease.
Increased reactive oxygen species (ROS) generation and the consequent oxidative damage are involved in the development of several diseases, including autoimmune diseases. Graves' disease is an autoimmune disorder characterized by hyperthyroidism and, less frequently, orbitopathy. Hyperthyroidism is characterized by increased oxidative stress. Untreated hyperthyroidism is associated with an incr...
متن کاملGraves' Orbitopathy
1Division of Endocrinology and Metabolism, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka 830-0011, Japan 2Department of Medicine, Nepean Clinical School, Nepean Hospital, The University of Sydney, Penrith, NSW 2751, Australia 3Molecular Thyroid Research Laboratory, Department of Medicine I, Johannes Gutenberg University (JGU) Medical Center, 55101 Mainz, Germany ...
متن کاملMedical Treatment of Graves’ Orbitopathy
▼ The medical treatment of Graves’ orbitopathy (GO) is usually reserved to moderate to severe disease. Steroids have been widely employed and possess anti-inflammatory activity, but about 20–30 % of patients are not responsive and about 20 % present with disease recurrence. Immunosuppressive therapy alternative to corticosteroids may target the different antigens involved in pathogenic mechanis...
متن کاملMedical Treatment of Graves’ Orbitopathy
▼ The medical treatment of Graves’ orbitopathy (GO) is usually reserved to moderate to severe disease. Steroids have been widely employed and possess anti-inflammatory activity, but about 20–30 % of patients are not responsive and about 20 % present with disease recurrence. Immunosuppressive therapy alternative to corticosteroids may target the different antigens involved in pathogenic mechanis...
متن کاملGraves’ orbitopathy as a rare disease in Europe: a European Group on Graves’ Orbitopathy (EUGOGO) position statement
BACKGROUND Graves' orbitopathy (GO) is an autoimmune condition, which is associated with poor clinical outcomes including impaired quality of life and socio-economic status. Current evidence suggests that the incidence of GO in Europe may be declining, however data on the prevalence of this disease are sparse. Several clinical variants of GO exist, including euthyroid GO, recently listed as a r...
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ژورنال
عنوان ژورنال: European Thyroid Journal
سال: 2020
ISSN: 2235-0640,2235-0802
DOI: 10.1159/000509615